In the game between the San Francisco 49ers and Chicago Bears on Sunday, Dec. 28 at 8:20 p.m. ET, our computer model expects the 49ers to come away with the victory. Looking for projections on the final score, spread, and point total, too? Find a complete game projection below.
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49ers vs. Bears Game Info and TV Channel
- When: Sunday, December 28, 2025 at 8:20 p.m. ET
- Where: Levi's Stadium in Santa Clara, California
- TV: NBC/Peacock
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 107.7 The Bone
49ers vs. Bears Odds and Betting Info
- Spread favorite: 49ers (-3.5)
- Moneyline: 49ers (-193), Bears (+160)
- Total: 51.5 points
49ers vs. Bears Prediction
- Pick ATS: 49ers (-3.5)
- Pick OU: Under (51.5)
Prediction:
49ers 30 - Bears 18
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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49ers vs. Bears Betting Insights
- The 49ers are 10-5-0 ATS this season.
- The Bears are 10-5-0 ATS this season.
- San Francisco has an ATS record of 5-0 when playing as at least 3.5-point favorites this season.
- Chicago has covered the spread twice this season (2-2 ATS) when playing as at least 3.5-point underdogs.
- In the 49ers' 15 games this season, the combined scoring has gone over the point total nine times.
- In 2025, seven Bears games have hit the over.
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